Targeted therapies are the drugs which are designed in order to interfere with the specific molecules necessary for the tumor growth and progression. The traditional cytotoxic chemotherapies mostly kill the rapidly dividing cells in the body by interfering with the cell division while causing the toxicity in normal cells also. This review article aims to highlight the most recent FDA-approved anticancer drugs eligible for targeted therapies. In addition, an early outline evaluation of the costs of the therapies was also taken in consideration. Moreover, further studies have been going on in order to plan treatment regimen for these drugs. On the basis of these fields, the oncologists will have new means to make treatment decisions for their patients in order to maximize benefit and minimize toxicity