Abstract: The purpose of this study was to investigate the chemical composition of the essential oil from salvia officinalis collected from north east of Algeria. The oil was isolated by hydrodistillation in a Clevenger-type apparatus and analyzed by GC/MS. The yield of the essential oil was 1.48% (v/w) and thirty seven constituents were identified according to their chromatographic retention times and mass spectra, corresponding to 100% of the compounds present. The major constituents of the oil were caryophyllene (25.87%), 1-alpha- Terpineol (16.85%), (+)-Ledene (10.05%) and Allo-aromadendrene (6.99%). The essential oil studied was not similar to those found in the literature; however, the main compounds of this oil present several interesting biological activities.