The dermatoglyphics is the study of epidermal ridges present on the surface of palm, soles, finger and toe and have emerge a promising tool in screening and diagnosis of medical and genetics conditions. It is one of the low-cost and noninvasive methods used for mass screening. Materials & methods: This study was conducted out in 100 diabetes mellitus (DM) patients and 100 Non diabetic individuals as control. Dermatoglyphic prints of both hands of study subject were taken by using ink method as described by Cummins and Midlow. Results: This study observed that whorls are increased in diabetic patients both in right and left hand, this difference was found statistically significant (p<0.0001, p<0.003). Arches found more in control than diabetes mellitus patient and this difference is statistically significant (p< 0.007, p<0.0001) Ulnar loop found more in control than diabetes mellitus patients and this difference found statistically significant. There was increase in ‘atd’ angle in patients of diabetes mellitus than controls and this was statistically significant.