A study was conducted to assess effectiveness of structured teaching programme on knowledge regarding psycho social interventions for the caregivers on caring the mental health needs of mentally ill inmates. The study was conducted in Shivamoga Beggar Relief and Rehabilitation Centre. Total samples were 10. Non probability purposive sampling technique was used. A structured questionnaire was used as an instrument to measure the level of knowledge of caregivers. It was seen that the pre - test mean (6.8+_2.7) was lesser than post – test mean (23.7+_1.9). Here p value is (<0.001*) which is highly significant. The study revealed that the 60% samples had poor knowledge and 40% of them had average knowledge in pre- test. But in post-test 80% of samples had excellent knowledge and 20 % had good knowledge. The study concludes that structured teaching programme was effective in improving the knowledge of caregivers regarding psycho social interventions. We have performed Fishers exact test to know the significant association between knowledge and selected demographic variables. We observed that there is no significant association between knowledge and selected demographic variables.