Fractures fixation with open reduction and compression plates is frequently used in diaphyseal radius/ulna fractures because of advantages like proper alignment, maintaining length and rotational alignment. This study compares the outcomes of treatment of fracture cases with dynamic compression plates and intra-medullary nailing by a square nail in mid shaft radius/ulna fractures. The study was conducted in Rajiv Gandhi Institute of Medical Sciences, [RIMS] Adilabad during the period from March 2014-Dec 2017. The study involved n=55 cases of which n=31 were male and n=24 were female. The common age group involved was 31- 40yrs contributing to 41.81% (n=23) of cases followed by 23.63 % (n=13) cases in 21 -30 yrs age group and 20% (n=11) cases in 41 – 50 yrs age group. Most common type of fracture was Transverse type in 37 cases, oblique in 10 cases and comminuted in 8 cases. Dynamic compression plates were used in 61.82% (n=31) of cases, IM nail was used in 38.18% (n=24) of cases. Dynamic compression plate treated patients had overall 94.11% cases in Excellent and good results and 90.48% of the IM nail treated patients had excellent and good results. To conclude Treatment of diaphyseal forearm is challenging as it because of lack of censuses regarding treatment and it requires judicious selection of cases for using compression plates or IM nail. Within the limitation of the present study, it may be concluded that dynamic compression plate offers better overall outcomes in the treatment of diaphyseal radius/ulna fractures