Abstract: Stroke is an emergency condition in which blood supply get effected and blood flow to brain stops and brain cells starts to die. Stroke is a second leading cause of hospitalization during Hajj. There are six types of stroke. There are many risk factors which may lead to stroke during Hajj such as cardiovascular diseases, hypertension, hypercholesterolemia, depression, atrial fibrillation, increased volume of heart, angioplasty, elderly, renal disease, calcium and fat deposition in heart vessels and rheumatic fever etc. Our survey aims to find its awareness in pharmacy undergraduates. A cross sectional and random sampling method was used to collect data in the month of August and September 2015. Data was collected from 100 pharmacy undergraduates from Karachi, Pakistan. According to our survey 100% pharmacy undergraduates have basic knowledge about stroke, 58% have awareness about the second leading cause of hospitalization during Hajj, 74.5% have knowledge about types of stroke and 69.9% have awareness about the risk factor of stroke during Hajj. 88% pharmacist have knowledge that how to prevent stroke during Hajj. We concluded that there is lack of awareness. Steps should be taken to spread its awareness in layman.