Most people consuming alcohol, weather in moderate or large quantities also take medications which may be a prescription based medicine or a over the counter medications at least occasionally causing serious possible interactions. The aim of our study was to characterize the adverse outcomes associated with alcohol and alcohol interacting medications in patients. A questionnaire survey was conducted for a period of six months in Urban health centre with a sample size of 500. All adult and older adults male patients taking alcohol who were on medication for chronic conditions and male Patients who are of age between 30-75 years were included in the study. Data I0IOthe questionnaire was analyzed using appropriate statical tools. POSAMINO criteria was used to assess the potential alcohol drug interactions. In the study population, 40.8% of participants belonged to age group of 41-50. Majority of 60% participants were consuming alcohol weekly 60% of the study participants were consuming alcohol since past 5-10 years. Sixty percent of the participants do not miss there dose after consumption of alcohol. Almost 60% of the participants were not injured after consumption of alcohol. twenty percent of the participants were having potential alcohol drug interactions with anti diabetics drugs were as 20% of the participants were having potential alcohol drug interactions with anti hypertensive drugs, Our study found considerable alcohol- medication interaction. There is a need for educating the people regarding stopping of alcohol consumption while on medications.