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Saudi Journal of Medicine (SJM)
Volume-6 | Issue-12 | 428-434
Original Research Article
Whole Body Mr-Dwibs vs. [18F]-FDG-PET/CT in Oncology Patients Coming to Pravara Rural Hospital, Loni
Dr. Prerna Ajwani, Dr. Yogendra Pishorilal Sachdev, Dr. Ganesh Vikhe, Dr. Manohar Pravin Sachdev
Published : Dec. 26, 2021
DOI : 10.36348/sjm.2021.v06i12.006
Abstract
Background: Over the past twenty years, advances in our understanding of tumour biology have led to the development of improved treatment strategies for many cancers. As a result, many patients are living longer with metastatic disease and the incidence of metastasis is continuing to rise. Based on post-mortem findings, approximately 70% of patients with breast or prostate cancer have bone metastases. Commensurate with the increased prevalence of bone metastasis, there is potential for significant comorbidities such as pain, limited mobility, hypercalcaemia, spinal cord or nerve root compression, myelosuppression and pathologic fracture. Therefore, early detection of skeletal metastasis is critical for accurate staging and optimal treatment; to allow the implementation of treatment strategies such as surgical fixation, radiotherapy, or bisphosphonate therapy to reduce the risk of complications and improve quality of life. Material and methods: The evaluation of diagnostic tests was carried out on50patients in the Department of Radiodiagnosis, Rural medical college, PIMS (D.U) Loni for duration of 2 years (2019-2021). Study population included all patients referred to Department of Radiodiagnosis for DWIB to look for metastases. The ethical clearance was obtained from the Ethics Committee, Rural Medical College and Hospital, Loni. All the patients fulfilling the selection criteria were explained about the purpose of study and a written informed consent was obtained to participate in the study before enrolment. Results: In our study out of 50 patients, 29 were males and 21 females. The most common age group were of 40 to 50 yrs. The sensitivity of DWIBS was 97.87%, specificity was 100%, positive predictive value of 100%, negative predictive value of 75% and accuracy was 98% in detecting metastases. Conclusion: Present study concluded that MR-DWIBS is useful in detection of metastases in patients with a low level of suspicion and normal or nonspecific and [18F]-FDG-PET/CT finding. DWIBS is a radiological modality devoid of radiation exposure like with [18F]-FDG-PET/CT. MR- DWIBS is a particularly useful modality in diagnosing metastases due to its high specificity, and accuracy as compared to [18F]-FDG-PET/CT.
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