Chronic hepatitis C virus (HCV) and diabetic mellitus (DM) are two public health issues that have a significant financial impact on health-care systems. Hepatitis, cirrhosis, and hepatocellular cancer are all symptoms of HCV infections. They've also been linked to the pathogenesis of extrahepatic symptoms, such as metabolic illnesses like diabetes mellitus. Longitudinal and cross-sectional studies have found that people with chronic HCV infections had a greater incidence and prevalence of diabetes than those of HBV sufferers. Chronic HCV infections are accelerated histologically and clinically and lead to Diabetes mellitus. With the development of novel treatments like as direct-acting antiviral agents that enhance glycemic control in these individuals, therapy has recently progressed.