Nutritional rickets caused mostly due to Vitamin D deficiency. It is has been declared a public health problem for both adults and children worldwide. Wheezy chest and related allergic diseases are the leading causes of morbidity in children. The objective of this study was to investigate the potential relation of vitamin D deficiency and wheezy chest in children. Case series study was conducted during the period from January to March 2021. 50 children aged 3 months to 24 months were selected randomly from children admitted to department of pediatric in Al-bieda medical center. Out of the total 56% were males, 70% were exclusively breastfed in their first 6months of life. 68% have positive family history of chest allergy. (64%) developed first attack of wheezy chest before 6 months and recurrent attack were observed in (52 %). Vitamin D deficiency was observed in 62% of the wheezy patients with 56% of cases had minimum sun exposure. Early onset was more common in males. Late onset wheezy chest was more common in children lives in houses with bad ventilation in compare to those who lives in better conditions in conclusion, vitamin D deficiency was common finding among children included in our study. It was associated with minimum sun exposure and early weaning. However, larger follow up studies are required to elucidate the effect of vitamin D supplementation on different parameters of asthma severity, its potential therapeutic benefit on children suffered recurrent wheezy chest attacks