Animal diseases can easily be transmitted into human by some causative agents and it has great economic losses in the universe. Fowl Cholera is a chronic disease caused by Pasteurella Multocida which basically effects the joints, wattles, infraohits, sinuses and other tissues. Fowl Cholera disease is transmitted by discharges from the carrier birds, cannibalism of the dead birds or infected droppings, as well as by dirty feedstuff, equipment, clothing, water. Infectious Bronchitis disease is widely spread disease and it causes serious deaths in flock and it covers half of flock in minimum duration of time. Capri poxvirus is a viral disease and it has three different mode of infection which effects on ruminants such as sheep pox, the goat pox and the lumpy skin disease. Capropoxvirus has several modes of transmission in living organism through mating, aquatic life animals and from animal to animal which causes necrotic lesion or death of tissues in chronic cases of virus. Sheep pox and goat pox are diseases of small ruminants with contagious viral infections. This viral disease has harmful impacts on sheep and goats in endemic areas. Lumpy skin disease (is actually skin problems created viral disease which mostly shows infection in cattle and water buffalo. Rift Valley fever (RVF) is a viral zoonosis which effects animal at initial stage and then have capability to transmit in humans.