Background: morphometric analysis of the thyroid gland alters with age, sex, race, and geographical location. The Ellipsoid method also has accuracy in evaluation of thyroid volume. Aim: to study the morphometric analysis of thyroid gland and its volume by ellipsoid method. Materials and Methods: 30 (Male-23; Female-7) cadavers with age range 55- 60 years were utilized from the Department of Anatomy, Santhiram Medical College, Nandyal to study the morphometric parameters of adult thyroid glands. The morphometric parameters like length, width, thickness and weight of the glands were measured and recorded. The volume of the thyroid gland calculated by the ellipsoid method by using morphometric parameters. The formula for evaluation of thyroid volume by ellipsoid method (π / 6 x Length x Width x Thickness) of the thyroid gland. Results: The weight of the thyroid glands was 14.02+ 0.51gms in males and 13.94+ 0.55gms in females. The average weight of the male thyroid glands was more compared to female thyroid glands in the present study. The length of the thyroid glands was 4.20+ 0.19 cm in males and 3.95+ 0.15cm in females. The width of the thyroid glands was 6.2+0.12cm in males and 6.11+ 0.14cm in females. The thickness of the thyroid glands was 1.43+ 0.07cm in males and 1.40+ 0.05cm in females. The Thyroid volume was 17.95+1.45 ml (CF: 0.479); 19.59+1.53 ml (CF: 0.524) by ellipsoid method. Male thyroid volume was more compared to the female thyroid volume in the present study. Conclusion: The ellipsoid method of evaluation of thyroid volume to be further correlated with fluid displacement method in understanding morpmetric analysis of the thyroid gland.