Accomplishing any jumbled task demands organization, coordination, and discipline. Overseeing a Bioequivalence study is certainly in the same manner, to guarantee that the trial works successfully, good project management is necessary. Project Management in a CRO necessitates competence in a variety of areas, including time, quality, cost, scope, risk management, communications, and sponsor management, and many others. The current review focuses on how to plan each phase of the study and how to create an effective Project Management Plan to reduce the average duration of the study and project management risks. The review also advises to follow a standard operating procedure at all times when conducting Bioequivalence study.