Consumer protection in electronic commerce transactions is an essential component of any economic system. It is all about making sure that the consumers’ rights are protected by providing mechanisms for reparation of damages in case of infringement, be it in the provision of services or products. For example, consumers who fall victim of defective products or to identity theft can be harmed by having their privacy invaded, suffering the psychological stress of having their reputation ruined, incurring financial liabilities, and undergoing tremendous transaction costs to restore their names. In this vain, this paper aimed at making an appraisal of jurisprudential and legal instruments governing e-commerce transactions in Cameroon with particular emphasis on matters of online contracts for sales of goods and services. The paper also provide modest solutions for the hurdles facing Cameroonian consumers in establishing contractual liability both at the regional (through the Organization pour l’Harmonization en Afrique du Droit des Affaires (OHADA, the Organization for the Harmonization of Business Law in Africa OHBLA) and national level. The paper therefore, concludes with some salient recommendations to bridge the gap between theory and practice in electronic commerce transactions in Cameroon.