Haya: The Saudi Journal of Life Sciences (SJLS)
Volume-6 | Issue-07 | 135-142
Original Research Article
Clinical Efficacy of Placental Derived Membranes in Treatment of Gingival Recession- A Systematic Review
Dr. Sumbul Bashir, Dr. D. Gopalakrishnan, Dr. Santosh Martande
Published : July 9, 2021
Abstract
Scientific rationale for the study: Gingival recession is a condition causing functional and esthetic disturbances and has a high prevalence rate. A wide range of surgical techniques and membranes have been proposed through the decades for recession coverage. Amnion/ chorion membranes are rich in type I, IV, V, and VI collagen, proteoglycans, laminin, and fibronectin, demonstrating properties of wound protection, pain reduction, and effect on epithelialization and being bacteriostatic in nature. The available evidence suggests that Coronally Advanced Flap (CAF) combined with amnion/chorion membranes has significant effect on gingival recession, gingival phenotype, gain in clinical attachment level, increase in Width of Keratinized Gingiva. Therefore the placental allograft is a viable alternative option for root coverage procedure in cases where there is a lack of autogenous connective tissue available to treat gingival recession defects or the patient is unwilling for a second site of surgery. Principal findings: The available evidence suggests that Coronally Advanced Flap (CAF) combined with amnion/chorion membranes has significant effect on recession coverage, gain in clinical attachment level, and increase in Width of Keratinized Gingiva. The membrane has also shown to be effective on the gingival biotype, changing to a thick biotype. Practical implications: The placental allograft is a viable alternative option for root coverage procedure in cases where there is a lack of autogenous connective tissue available to treat gingival recession defects or the patient is unwilling for a second site of surgery.