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Scholars International Journal of Anatomy and Physiology (SIJAP)
Volume-4 | Issue-06 | 90-92
Original Research Article
A Comperative Study of Serum Creatinine, Serum Uric Acid and Blood Urea in Normal Pregnant and Pregnancy Induced Hypertensive Subject
Dr. Harsida Gosai, Dr. Urmila Pateliya
Published : June 30, 2021
DOI : 10.36348/sijap.2021.v04i06.006
Abstract
Background: Pregnancy induced hypertension also known as Preeclampsia clinically is one of the commonly seen complication in pregnant women. It contributes to the cause of maternal and peri natal morbidity and mortality. According to some study, serum creatinine, Blood urea, serum uric acid level increases during pregnancy induced hypertension. Preeclampsia is associated with renal function impairment. The objective of this study is to compare serum creatinine, Blood Urea and Serum Uric acid in preeclampsia with normal pregnancy. Materials and methods: The study was performed on 86 pregnant women. Out of which 50 women were pregnancy induced hypertensive and 36 were normal pregnant women. Result : The result showed significantly high blood pressure (SBP-160.0±18.8 VS 112.64±8.19, DBP 110.68±9.55 VS 76.8±4.14)and Blood urea ( 16.56 ±1.72 mg% VS 22.25±1.28 mg%), serum creatinine ( 0.72 ±0.19 mg% VS 1.09±0.34 mg%), serum uric acid level ( 4.63±0.19 mg% VS 7.04±0.4 mg% )in pregnancy induced hypertensive women compares to normal pregnant women. In the present study, in pre-eclampsia, there is elevation of serum uric acid and serum creatinine elevated values are statistically significant. Conclusion: There is a renal derangement of parameters in preeclampsia so it may be advised to renal function test to confirm involvement of renal dysfunctions. Measurement of renal function Test could be used as a biochemical indicator in pregnancy induced hypertensive women.
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