Background: The term urethral stricture refers to anterior urethral narrowing or a scarring process involving the spongy erectile tissue of corpus spongiosum. Urethral stricture is one of the most important causes of bladder out flow obstruction. There are different treatment modalities for the management of stricture urethra. Both the patient and the physician must have a good understanding of the procedure & outcome of treatment. Different types of tissues are standardized by different surgeons. Each type of graft has its own procedural advantage and disadvantage. So it is recommended to select the case for a particular type of graft. But it is evident that judicious use of specific graft has almost equal outcome. Aim: To see outcome of substitution urethroplasty in the management of long segment anterior stricture disease, to study the improvement of clinical manifestation (poor flow, narrow stream, double stream) following surgical correction of stricture urethra And to see the change in uroflowmetry following surgical correction of stricture urethra, to study the post-operative complication. Methodology: This study comprises of 50 consecutive cases of anterior urethral stricture who were admitted in department of urology Enam Medical College and Hospital from January 2018 to January 2021. All patients were attended in urology outpatient department. They were worked up properly and previous treatments were thoroughly analyzed. All of them were appropriately treated with reconstruction. The total study population was 50 patients aged 20-50 years. Results: The total study population was 50 patients aged 20-50 years, 8(16.0%) patients had 20 years to 25 years, 16(32.0%) patients had 26 years to 30 years, 10(20.0%) patients had 31 years to 35 years, 8(16.0%) patients had 36 years to 40 years, 3(6.0%) patients had 41 years to 45 years and 5(10.0%) patients had 46 years to 50 years. Average Mean value of Peak flow rate in first month in 50 patients was 29.78ml/sec. Cystoscopy was done in all patients in 3rd month to see the anastomotic site. After six months of follow up only two patients had complaints of obstructive symptom. Uroflowmetry showed peak flow rate less than 10 ml. Here we did cystoscopic examination. And stricture segment was identified proximal to the previous site which was managed by OIU. After that no such obstructive flow was reported by those patients. Retrograde Urethrogram was done in all the patients to see caliber of urethra. In case two out of 50 showed recurrence in RGU with MCU. Conclusion: This study showed better outcome than any other conventional method for the treatment of stricture urethral disease. So, it can be concluded that substitution urethroplasty is the treatment of choice for the management of long segment anterior urethral disease.