Introduction: Fusion of the vertebrae known as vertebral synostosis or vertebral block. It is a interest of the anatomist but also to surgeons, neurologist, orthopedician, radiologist, anaesthetics and for forensic medicine also. Any defect in the development causes anomalies and neurological sign and symptoms. Various vertebral anomalies have been reported by different authors such as Sacralisation, Lumbarisation, Occipitalisation, absence of posterior elements of vertebral arch and vertebral synostosis. Methods: The present study was conducted on 400 dry adult human vertebrae of unknown age & sex obtained from department of Anatomy of medical college of Gujarat. Result: Fusion of the first right rib with the first thoracic vertebrae. Axis vertebrae fuse with the third cervical vertebrae. Five Thoracic vertebrae in one thoracic spines,were fuseb along with one right rib and four left rib fused with thoracic vertebrae. Two typical thoracic vertebrae fuse in one thoracic spine. Seven vertebrae fuse with each other, lower thoracic and upper lumber vertebrae fuse with each other. Twelth rib fuse with the twelth thoracic vertebrae in one spine. Sacralisation of L5was observed in one spine. Conclusions: Knowledge about any deviation from the normal anatomy of vertebral column can lead to major or minor complications affecting the different system of the body. Fused vertebrae limit movements and cause signs of nerve or spinal cord compression. This variation must be noted by surgeons, neurologist, orthopedician, radiologist, anaesthetics.