Objective: Determine the Practice of self-prescribed analgesics from the students of physical therapy. Methodology: 150 students of physical therapy were selected to be a part of the study through randomized sampling. All of them were informed of the study and after taking verbal consent were asked to fill a questionnaire pertaining to self-prescription. Data was analyzed using SPSS Version 20.0.The Chi Square test was applied to determine the statistical significance which was kept at P=<0.05. Results: 77(51.3%) male candidates and 73 (48.7%) female candidates in our study of 150 physical therapy students showed that there was no significant difference in self-prescription of systemic analgesics with P=0.156. Conclusion: The prevalence of Self-prescription was found to be high among physical therapy students. Better regulation of over the counter medicines and efficient counseling is highly necessary to reduce the amount of self-medication ongoing.