Background: Hemoglobinopathies including Thalassemia with an estimated 10,000 live births each year and Sickle cell disease (SCD) with an estimated 5,200 live births each year, are a major public health problem in India specially in scheduled tribes, who have a high prevalence of socio-economic disadvantage and are frequently medically underserved [1]. In Bastar, the land of tribes as about 70% of population comprises of tribals, which is 26.76% of the total tribal population of Chhattisgarh [2]. Hence this work was an attempt to compare anthropometrically between Sickling and Non-Sickling individuals of tribal population of Bastar Division, Chhattisgarh. Aims & Objectives: To compare anthropometrically between sickling and non-sickling individuals of tribal population of Bastar division, Chhattisgarh. Material and methods: An observational case-control study of 138 sickle cell disease patients with electrophoresis/sickle solubility test positive, aged 5yrs to 30yrs and 138 sickle solubility negative age and sex matched controls was done. Anthropometrical parameters like height, weight, upper and lower limb lengths were statistically compared. Results: In males, in the age group of 5-14yrs, the parameters that were statistically significant were of axial skeleton and limb lengths. This suggests that it is the most vulnerable group. In the age group of 20-30yrs the parameters that were statistically significant were hemoglobin concentration (p<0.0001), weight (p=0.004), maximum calf circumference (p=0.02) and BMI (p=0.02). In females, statistically significant difference for hemoglobin concentration between the cases and controls in all three age groups was seen i.e.,5-14yrs(p=0.05), 15-19yrs(0.001), 20-30yrs (p<0.0001) and in the age group of 15-20yrs, t-test for weight between cases and controls in female group showed significant difference (p= 0.01). Conclusions: From the above results and low SES, it may be stated that the poor growth status of the cases may be due to the SCD and poor socio-economic conditions.