Background: Clomiphene citrate is an orally active nonsteroidal triphenylethylene derivative, commonly used for ovarian stimulation; it is an ovulation inductor, an important tool in various assisted reproduction treatments. The side effects are unusual however they are listed in the OHSS ovarian hyperstimulation syndrome, which is an exaggerated response to excess hormones that can lead to significant complications. Case presentation: This is a case is about a unilateral adnexal torsion secondary to clomiphene citrate’s stimulation, without associated pregnancy which was managed in our department of gynecology in the maternity of Rabat. Conclusion: The ovarian hyperstimulation syndrome is becoming more common as the number of women undergoing in vitro fertilization increases. A worsening of the symptoms of OHS can still normally be managed in outpatient form, but can also have serious complications resulting from are much less common and can involve risk to life.