Antiplatelet drugs are recommended globally for long term prevention of serious vascular events in high risk patients. Temporary withdrawal of these drugs seems to be an attractive option in dental office prior to minor surgical procedures to prevent a bleeding hazard. The benefit of averting anti-platelet drug induced hemorrhage needs to be balanced against the risk of potentially fatal thrombosis that may occur due to rebound phenomenon after withdrawal of the anti-platelet drug. This in-vivo prospective study was thus designed to assess post-operative bleeding in patients on aspirin therapy after extractions. The study sample comprised of 50 patients between 50 to 75 years of age on long term aspirin therapy requiring extractions were assessed for bleeding at 30 mins, 1, 2, 3, 24 and 48 hours post operatively. Results showed 4 patients had mild bleeding at 30 mins, 2 patients at 1hour, 1 patient at 2 hours and no patients with bleeding at 3 hours. In our study we had an 8% risk of bleeding after extractions in patients on long term low dose aspirin therapy. Given the low incidence and severity of bleeding which can be easily managed by local measures only, we conclude that patients need not discontinue taking aspirin prior to dental extractions.