Oral ingestion is the preferential route for various drugs, providing an acceptable technique to consummate both local likewise systemic effects. SRDDS designed to ease off drug at a fixed rate by upholding a constant drug level for a definite period of time with decrease side effects. The fundamental reasoning of SRDDS exemplifies the pharmacokinetic, pharmacodynamic and biopharmaceutical effects of a drug so that it utility is increased, reduced the side-effects and control the disease. Nowadays research and development are carried out on sustained release formulations due to its inherent benefits over conventional dosage form. The main objective of the review, we discuss the sustained release tablets, its rationale, challenges, advantages, disadvantages, various polymers used in the preparation, of these formulations. This system gets easy to adopt for designing to treat various diseases thereby it improves patient compliance.