Background: Drug utilization studies conducted at regular intervals help to guide the physician in prescribing drugs rationally. Methods: This is prospective, observational study was conducted in the outpatient of department of general medicine of Indian Institute of Medical Science & Research a tertiary care teaching hospital. Data was collected from patients who have been diagnosed with hypertension as per JNC-8 guidelines and patients receiving or prescribed with antihypertensive medications were included. Frequency and proportions of utilization of antihypertensive medications in were figured. Results: A total of 170 prescriptions were analysed during the 6 month study period. The patients 93 (46.5%) were on Mono therapy significantly higher than dual therapy, triple therapy and poly therapy, 64 (32 %), 27 (13.5%), 16 (8 %) respectively. Calcium channel blocker was the frequently used class of drug for monotherapy (19.5 %). In dual drug therapies were CCB+ARB accounting for 18.5 %, and 5.8% of patients were on triple drug therapy with CCB+ARB+Diuretic. 30.2% patients were on ACE inhibitors. 25.5 % patients receiving Calcium channel blocker reported side effect. Conclusion: This type of studies gives the base line idea of prescription pattern and ADRs of antihypertensive drugs. These helps to design policy for rational use of drugs and motivation of physician for rational use of drugs. The study emphasizes that need for effective continuing medical education and also preventive measures in hypertensive individuals.