The biosensor tool which is used in the fields of area of a good life such as research related to medicine, public health-care , in the monitoring of the environment, now a days scientist make more advancement. The modification in the field of technology which is really helpful in the making of the biochip and they provided all of the instrument needed to require make a detection tool, and a system with the micro fluid are place on the chip, sampler, probe, amplifier, detector, and a logic circuit and these biosensor provide the simple, reagent free, label free, monitoring with real time and application with the low cost. In the field of medical this would be very helpful in the production of the low cost detection of the analytic and use in the home such as the glucometer which tell us about the blood glucose concentration and can accordingly administrate the concentration of the insulin in the body, the detection of the disease becomes more easy as we cannot send the sample for the detection in the laboratory which is really time consuming and costly procedure. In the field of environment monitoring biosensor can detect the various target present in the environment, beside from the specialized laboratories and the devices which is portable and development research step from the initial form to its product which require the intention and the collaboration of the different science and technology universities and many other institute of research, stake holder and investor should also pay intention toward the development of these kind of technologies.