Saudi Journal of Oral and Dental Research (SJODR)
Volume-2 | Issue-12 | 296-302
Original Research Article
Clinicopathological Parameters and its Correlation with Recurrence, Distant Metastasis and Death Rate in Oral Cancer a Retrospective Study
Dr. Kavya BT, Dr. Mubeen Khan, Dr. Vijayalakshmi KR
Published : Dec. 30, 2017
Abstract
The incidence of oral squamous cell carcinoma remains high in India due
to the social and cultural habit of tobacco, it accounts for about 5%of total cancer of
the body. Despite evolution in management,the overall survival of patients has not
been improved significantly during the past 20 years. Several clinicopathological
parameters have been implicated in the prognosis, recurrence and survival, following
oral cancer. This retrospective study aims at the study of clinicopathological
parameters including regional lymph nodes and distant metastasis and its correlation
with recurrence and death rates in patients with oral squamous cell carcinoma. In this
retrospective study data collected from the registry of cancer ward, Victoria hospital
and Government dental college, Bangalore from 2007-2014(8 years) in total, 283
patients with oral squamous cell carcinoma were included. The clinical staging and
histopathological reports were analysed and chest X ray, MRI was used to assess the
distant metastasis and these findings were correlated with recurrence and death rates
of the patients.Statistical analysis was carried out using chi square test. Among 283
patients 159 were males (56.2%) and 124 were females (43.8%). Most of the
identified squamous cell carcinomas were T4 (42%) and N2 (40.6%). Recurrence was
identified in 40 patients, 85(30%) had regional nodal metastasis and 9 had distant
metastasis, and 40 patients died out of 283.Squamous cell carcinoma of the oral
cavity has a poor overall prognosis with a high tendency to recur at the primary site
and extend to involve the cervical lymph nodes.