Unsustainable agricultural practices pose a serious threat to the integrity of landscapes and availability of soil mineral nutrients to plants. The phenomenon is compounded by changing global climatic conditions. This paper examines the potential role of agroforestry in mitigating changes due to undesirable human behaviour in the once forest dominated western highlands of Cameroon. Data were elicited from existing literature on agroforestry, landscape management, forestry, and subsistence agriculture. Findings lend credence to the fact that agroforestry systems constitute a promising option for maintaining the stability of landscapes and soils that are subjected to human activity. Aside from the major systems namely agro-silviculture, silvo-pastoral, and agro-silvopastoral, there exist other agroforestry categories like aquaforestry, apiculture, and sericulture. Living fences, alley cropping, improved fallow, shelter belts, home gardens, and scattered trees on croplands were highlighted to be suitable agroforestry practices for the western highlands region of Cameroon.