Biodiversity loss through anthropogenic drivers is a matter of serious concern. Background extinction is a natural phenomenon. Anthropogenic biodiversity loss, also called sixth mass extinction has been addressed from various viewpoints. The issue of biodiversity loss has been discussed in local-, regional-, and national- and international –forums. The debate is continuing to identify the root cause of the anthropogenic mass extinction. The present communication discusses various anthropogenic drivers of biodiversity loss and explains the on-going sixth mass extinction using Garrett Hardin's “the tragedy of the commons”. Such explanations provide options for policy makers and for the people to save the precious biodiversity of our planet. It has been demonstrated that our present consumption of the Net Primary Productivity must be reduced through reducing consumption of food and energy to save the other life forms or the biodiversity. Promotion of sustainable human behaviours to ameliorate the problem of anthropogenic extinction has been discussed in the light of recent findings from neurobiology and molecular biology to give options for solving the problem. Biodiversity conservation through providing benefit to the people may be the effective conservation strategies which would save the interest of human civilizations as well as other life forms on the earth.