The study examined plant species whose barks were being extracted and used for health maintenance by the Ijaw tribal community of Bayelsa State of Nigeria. 150 respondents, randomly selected, were interviewed with the aid of a semi-structured questionnaire guide. All the interviewed were focused, conversational and two-way in communication. Plant species with medicinally valued barks were identified and information on them were obtained and documented. The results obtained revealed that the socio-economic status of the respondents were not prerequisites to their consciousness on the medicinal values of plants in their vicinities. Despite the availability of most of the species in the respondents’ environment, market patronage was still the preferred source as many of them could not recognize the species even with their vernacular names. Also a declining rate in the passage of ethno-botanical knowledge from one generation to another now abounds in the study area. Trading in medicinal barks was prominent and was dominated by the females who sourced their stocks from diverse areas. A total of 62 plant species, belonging to 38 families, were observed to have their barks valued for medicine for diverse diseases. The methods of preparations and utilizations of the plant-based medicine were simple and easily adoptable by the respondents. The extraction methods utilized sourcing for barks were mostly predatory and annihilative. Most of the indentified species were indigenous, uncultivated with poor regenerative abilities thus most of them were presently not abundant in the study area. Conservation measures that could enhance their sustainability were prescribed.