Six cyanobacterial strains were isolated from pesticide exposed paddy field soil by enrichment method. The isolate exhibited unicellular and filamentous character and are designated and identified as JMCTTKC1-Phormidium pachydermaticum, JMCTTKC3-Oscillatoria chalybea, JMCTTKC4-Oscillatoria tenuis, JMCTTKC5-Oscillatoria ornata, JMCTTKC6-Chroococcus dispersus and JMCTTKC7-Phormidium tenue. The effect of 0.05% of lambdacyhalothrin was analysed on chlorophyll-a and protein content of the cyanobacterial isolates in mineral medium at different time intervals. The maximum level of chlorophyll-a content JMCTTKC4-Oscillatoria tenuis-39.3500µg/mL and protein content JMCTTKC6-Chroococcus dispersus- 99.9µg/mL was recorded on the 9th day sample. At the same time decreased level of chlorophyll-a content JMCTTKC1-Phormidium pachydermaticum-3.8597µg/mL and protein content JMCTTKC3-Oscillatoria chalybea 24.73µg/mL was observed on 13th day sample. From this above observation it was clearly noted that the selected isolates are capable of degrading Lamdacyhalothrin pesticide and used its metabolites as a sole carbon and nitrogen source for their growth.