The present study was conducted on the crossbred Holstein cow presented with Bovicabovis infestation around the perineal and tail regions to establish new avenues in the field of therapeutic management of Bovicolabovis infestation in cows. The Kerosene oil was applied to the tail and perineum of the affected cattle and the area was subsequently washed with water. It was found that all the animals recovered well subsequently after the operation. The present study could be helpful for the field Veterinary Professionals in managing the cases of infestations of Bovicolabovis in cattlein an indigenous and cost effective way.