Nutrient canals are radiolucencies seen in the alveolar bone which are considered to be the channels that contain blood vessels and nerves supplying the teeth and the supporting structures. They are also called as circulating canals, interdental channels and vascular canals. They are predominantly seen on the intraoral periapical radiographs in the mandibular anterior region. Though they are considered to be normal, according to literature, some investigators have correlated the radiographic appearance of nutrient canals with certain pathologic conditions. Hence this study was undertaken to rule out the association as well as prevalence of nutrient canals in patients with systemic conditions like hypertension and diabetes.