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Saudi Journal of Medical and Pharmaceutical Sciences (SJMPS)
Volume-6 | Issue-08 | 530-534
Case Report
Toxic Epidermal Necrolysis: A Case Report on its Ophthalmic Complications and Management
Urmil Chawla, Nisha Bura, Vandana Sharma, Richa Sharma, Chugh JP
Published : Aug. 22, 2020
DOI : 10.36348/sjmps.2020.v06i08.003
Abstract
Steven-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are potentially life-threatening mucocutaneous diseases characterized by hypersensitivity to medication and infections. Inspite of complete recovery from skin problems without sequelae, survivors can land with serious ocular complications culminating in blindness irrespective of intensive local and systemic therapy. We are describing the clinical course and treatment of a patient with TEN who developed bilateral ankyloblepharon after recovery from the acute attack. Amniotic membrane was applied to the ocular surface of the patient after correcting the ankyloblepharon. Amniotic membrane transplantation (AMT) has been proven to be an effective mode of treatment for severe ocular surface and eyelid inflammation as it decreases the risk of ocular and visual sequelae. Early detection of complications and aggressive treatment of the same are essential for preservation of vision.
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