Eye is the most fantastic creation of God among all the sense organs in human body as it makes us aware of various objects all around us near and far. The eye is one of the most soft and most valuable of all the sense organs and is a challenging subject for topical administration of drug to the eye. Topical application of drug to the eye is the well accepted route of administration for the treatment of various eye disease like conjunctiva, eye flu etc. The eye as a portal for drug delivery is generally used for local therapy in order to avoid the risk of eye damage from high blood concentration of the drug which is not intended. The field of ocular drug delivery system is one of the most interesting and challenging task usually faced by pharmaceutical scientist/researchers. This field has significantly improved over the past 10-20 years.