The effect of leaf extract of Momordica charantia on sexual behaviour of male wistar rats was evaluated in this study. The animals were randomly divided into three (3) groups of six (6) rats each. Group one (1) serving as control received distilled water while, groups two (2) and three (3) received 200mg/kg and 400mg/kg of the hydromethanol (20%:80%) extract respectively. Parameters assessed included the mount frequency (MF), mount latency (ML), intromission frequency (IF), intromission latency(IL), ejaculation frequency(EF) and ejaculation latency(EL). Results showed that the parameters were not significantly altered after 30 days treatment with 200mg/kg and 400mg/kg extract. It was concluded that M. charantia may not affect sexual activity in male wistar rats within the administered doses.