Present study was carried out on adult Swiss albino mice of both sex, consisting of six groups with six mice in each group to find out additive analgesic effect of Hydro-alcoholic extract of Ginger with Paracetamol and also to find out additive analgesic effect of Hydro-alcoholic extract of Ginger with Ibuprofen by hot plate and tail flick methods. These six groups were, Groups-A paracetamol, group-B was Ibuprofen, group-C was distilled water, group-D (Hydro-alcoholic extract of Ginger, group-E (Paracetamol + Hydro-alcoholic extract of Ginger), and group-F (Ibuprofen + Hydro-alcoholic extract of Ginger). We find that Paracetamol, ibuprofen has analgesic effect of their own on mice but we did not find any significant analgesic effect of Ginger on mice in singly or additive analgesic effect in combination with ibuprofen or paracetamol. So, we may conclude that Ginger has no additive analgesic effect and no analgesic effect on single use also.