Background: The under recognition and consequent mistreatment of migraine headache highlight the importance of quicker and easy to apply tools for migraine screening and diagnosis. The ID migraine fits the description of such a rapid screening diagnostic tool. Objective: To evaluate the ID migraine, in migraine headache diagnosis, among clinical students in Calabar, Nigeria. Methods: Using a cross sectional design, we compared the performance of the ID migraine with that of the IHS criteria, used as a gold standard for migraine headache diagnosis, on a set of persons with recurrent headaches. Participants were recruited from a pool of 220 apparently healthy clinical students of the University of Calabar. Data analysis was done with SPSS version 20; and the level of significance was set as p < 0.05. Results: Fifty one persons who had recurrent headaches from the pool of students, comprising 25 (49%) males and 26 (51%) females, proceeded to complete the study. The mean age of the participants was 24.22 years ± 4.575. The sensitivity, specificity, accuracy, positive predictive and negative predictive values we obtained for the ID migraine tool were 69.2%, 63.1%, 64.7%, 39.1% and 85.7%, respectively (kappa = 0.258; p= 0.043). Conclusion: The ID migraine had moderate sensitivity and specificity in our locality, and a low level of agreement with the IHS criteria. Its usefulness in our locality may be more in ruling out, rather than ruling in, migraine in persons with recurrent headaches.