Saudi Journal of Medical and Pharmaceutical Sciences (SJMPS)
Volume-5 | Issue-09 | 810-812
Original Research Article
Incidence of Urinary Tract Infection, Identification of Pathogen and Drug Sensitivity Pattern in Children with Nephrotic Syndrome
Gobinda Mondal, Adyasha Mohapatra, Banasree Roy, Mala Bhattacharya
Published : Sept. 30, 2019
Abstract
Introduction: Nephrotic syndrome is primarily a pediatric disorder and it affects 1-3 per 100,000 children <16 years of age. The prevalence of UTI is high in nephrotic syndrome patients.UTI may be responsible for poor response to steroid therapy and it also induces relapses. Objectives: To determine the incidence of urinary tract infection, identifications of pathogen and antibiotic sensitivity pattern of UTI in children with nephrotic syndrome. Method: All nephrotic syndrome patients attending the OPD or Indoor who are fulfilling the criteria were included in the study. Detailed history was taken. Routine tests including the urine culture sensitivity were sent. Result: Incidence of UTI among nephrotic syndrome patients was18.75%. E.coli, Enterococcus, Klebsiella sp., Acinetobacter was the organisms. Commonest organism found was E.coli. Aminoglycoside group of drugs found to be the most sensitive (100%) followed by third generation cephalosporin (80%). Conclusion: UTI is not at all uncommon in nephrotic syndrome patients and all the patients may not present with classical symptoms. Hence a high degree of suspicion is essential for early diagnosis.