Saudi Journal of Medicine (SJM)
Volume-5 | Issue-04 | 198-204
Original Research Article
Clinical and Electrophysiological Correlation of Peripheral Neuropathy in Patients of Type 2 Diabetes Mellitus
Md. Eajaz Ahmed Shariff, Fahad Al- Qahtani
Published : April 21, 2020
Abstract
We evaluated the prevalence of peripheral neuropathy in type 2 diabetes mellitus (T2DM) by clinical examination and nerve conduction study (NCS), and to correlate them with risk factors. 58 T2DM patients attending OPD in the department neurology of Jubilee mission medical college hospital, Thrissur were evaluated. Grading of signs and symptoms were assessed by Neuropathy symptoms score (NSS) and Neuropathy disability score (NDS) followed by nerve conduction studies. Diabetic status was evaluated by HbA1c levels and patients were categorized Group I -HbA1c<5 (No diabetes), Group II- HbA1c= 5-7(Long standing controlled diabetes), Group III HbA1c >7 (Uncontrolled diabetes). 58 T2DM patients of which 42(72%) were males and 16(28%) were females and their mean age were 52.1±8.8 and 48.6±5.3 respectively. Clinical findings showed abnormal deep tendon reflexes in male 37(88%) and female patients 11(66%). Deep sensory loss was highest among male 39(92%) and female patients 12(75%) respectively. Loss of pain and touch sensation male and female patients were found to be 24(57%), 9(56%) and 35(92%), 12(75%) respectively. Atrophy of the muscles in male and female patients were found to be 13(30%) and 4(25%) respectively. Electrophysiological assessment showed 34(58.6%) patients in the severe group and score was 8. However mild and moderate patients were 3(5.1%) and 21(36.2%) and there severity score was 5and 6 respectively.T2DM patients has high prevalence of diabetic neuropathy. Motor nerve conduction abnormalities were severe in males with diabetic peripheral neuropathy. Motor mononeuropathy reflects more severe involvement and peroneal and ulnar neuropathy is well marked in these patients.