Dengue infection of humans occurs from bites of Aedes aegypti mosquitoes. The mosquito feeds during the day and has a propensity for man-made habitats containing water. Dengue viral infection can present as three broad clinical patterns: Classic dengue, Haemorrhagic fever and Undifferentiated fever. Clinically Liver is often enlarged and tender. There are many articles which has reported the involvement of liver in this disease. The changes can be noted both clinically and also biochemically in which the enzymes are quoted elevated. These features occur in both severe and non-severe dengue cases. Therefore, monitoring for warning signs and other clinical parameters is crucial for recognising progression to critical phase. This study puts in an effort to find the hepatic profile of the patients both clinically and biochemically so as to be useful to the practising physicians.