Background: The number of kidney, liver, heart and other organ transplants is growing rapidly, but not nearly as rapidly as the growth in the number of persons with defective organs who desire transplants. Also, cadavers are needed for Anatomy dissection classes for medical students. Methods: The study assessed the knowledge and awareness levels of 134 first professional MBBS students, who filled a prevalidated questionnaire. Observations and Results: Out of 134 students, 87.3% of the respondents were aware of the concept of organ donation while 12.7% had not even heard about it. 83.7%, 78.6%, 36.8% and 20.5% were aware about eye, kidney, whole body and liver donations respectively. Awareness of donation of other organs was found to be in the range between 11.9% and 7.7%. 48.7%, 29.1%, 14.2%, 9.4% and 1% of the aware respondents started that television, internet, newspaper, family members and other sources respectively were their sources of information regarding organ donation. Conclusions: Educating the public, supportive care, proper infrastructure, addressing various issues of organ and body donation - all these can help in improving the peoples’ understanding, and therefore increased rate of donation.