Background: Reflective practice is internationally recognised as a foundational mechanism for nursing professional development; however, no validated structural model links Gibbs’ Reflective Cycle to measurable clinical performance, evidence-based practice (EBP) adoption, professional competence, and patient safety outcomes among Saudi Arabian hospital nurses. The Gibbs Reflective Nursing Excellence Model (GRNEM) is proposed to address this gap. Objectives: This review synthesises peer-reviewed evidence (2021–2026) on: (1) the application of Gibbs’ Reflective Cycle among clinical nurses; (2) relationships between reflective practice and clinical performance, EBP, professional competence, and patient safety; and (3) the evidence base supporting GRNEM development and validation in Saudi Arabian hospital settings. Methods: A systematic review followed PRISMA 2020 guidelines. Six databases (PubMed, CINAHL, Scopus, Web of Science, MEDLINE, and the Cochrane Library) were searched for studies published between January 2021 and June 2026. Two independent reviewers screened 1,247 records; 24 studies met all inclusion criteria. Quality appraisal was performed using the Mixed Methods Appraisal Tool (MMAT) and Joanna Briggs Institute (JBI) checklists, with narrative and thematic synthesis. Results: Five overarching themes were identified: Gibbs’ Reflective Cycle as a structured professional development framework; reflective practice and clinical performance; EBP adoption in Saudi Arabian nursing; professional competence and nursing values; and patient safety culture in MNGHA and Saudi hospital settings. Structured reflective practice was consistently associated with improved clinical performance (k=9), EBP adoption (k=7), professional competence (k=5), and patient safety culture (k=3). Conclusion: Findings provide a robust evidence base confirming the theoretical plausibility, contextual relevance, and empirical foundation of GRNEM for Saudi Arabian tertiary hospital nursing, with implications for nursing education, clinical governance, and Saudi Vision 2030 health policy.