The physicochemical quality of the Tshopo River water before it enters the REGIDESO SA/Kisangani treatment plant in the Democratic Republic of Congo during the year 2024 was the subject of our research. The results show that the water quality of the Tshopo River does not differ significantly between quarters or between seasons in 2024, with p-values of 0.9647 and 0.9793, although there are noticeable differences between periods of heavy and dry rainfall. This is revealed by the results of analyses of more than seven physicochemical parameters, namely pH, turbidity, color, conductivity, temperature, oxidizable matter, and total alkalinity.