This work is about the brain chemicals, and their possible natural catabolic products. Effort has been made to identify if the microwave frequencies of these by products are same as the microwave frequency ranges of sodium and Potassium in ionic solutions present in as well as outside a neurone. It could be a factor responsible for dementia. It is found that excess by products of Tau fragment and Human prion peptide 2 had the same microwave frequency of sodium and Potassium in ionic solutions present in as well as outside a neurone. Therefore, it can affect the neuronal functioning. Efforts have also been made to identify, if any of these Brain chemical bind to each other and block the normal neuronal functioning. In this effort, it is noted that, excess of Human prion peptide 1 can bind to Tau-441 protein. This can affect neuronal function.