Saudi Arabia's Vision 2030 is a major transformative push for an economy and public services diversification such as in health. This strategic vision of health care in the Kingdom gives emphasis on sustainability, accessibility, and quality in the healthcare delivery systems. Developmentally, Jazan is a fast pace growing area which faces its own specific challenges and opportunities with respect to the provision of health services. This review intends to study the health care planning in Jazan in relation to Vision 2030 which includes key policy issues, infrastructure developments, technology integration, and human resources improvements. It draws conclusions on public-private partnerships (PPPs) for health, digital health initiatives, and strategic interventions to address health issues in the region. By peer reviewing the literature available, government reports, and case studies, this review is presented as an overview of best practices and recommendations for strengthening such systems in Jazan. In conclusion, critical aspects such as healthcare governance, financial investments, and technological advancement have been drummed up, emphasizing the need for Jazan to achieve the extensive healthcare goals set forth under Vision 2030.