To analyse the drug prescription pattern for secondary prevention of stroke, medication adherence, knowledge and awareness about the disease, and direct medical costs involved in the treatment of stroke. A Prospective observational study was carried out for 6 months in the inpatient department. The inclusion criteria of the present study are patients of either sex aged ≥ 18 years, patients who were diagnosed as stroke patients and admitted to the intensive care unit of the hospital. About 120 prescriptions in total were examined during the 6-month trial. Men aged 64 showed a higher prevalence of this (53.33%). 120 individuals were included in the study, 115 (95.5%) of whom had ischemic stroke, while 5 (5%) had a haemorrhagic stroke. Hypertension, dyslipidemia, and diabetes mellitus were the three main co-morbidities found; these conditions were present in 82 (68.0%), 80 (66.6%), and 73 (60.8%%) individuals, respectively. The majority of the patients in this study on pharmacological prescriptions for stroke were being treated with statin and antiplatelet medications. 109 (90.8%) of the 120 patients received statin (Atorvastatin) medication. This study found that clopidogrel, prescribed to 102 (84.8%) and 19 (15.8%) patients, was the most widely used antiplatelet. In our facility, the sole anticoagulant utilized for stroke victims was heparin.