This study involves the use of the histology of the mantle of a periwinkle species, Tympanotonus fuscatus, as a biomarker tool, to investigate and evaluate the ecological pollution status of two different water bodies, Bodo and Creek Road water-sides, in River State. The study involved the sampling of ten (10) feral table sized fish from two stations along the creeks of the experimental sites (Bodo and Creek Road water bodies), with similar specie, size and number from a reference site (ARAC – African Aqua-culture Centre). The test fish mantles were harvested from the fish caught from both experimental sites for histological evaluation, while the control mantles were harvested from fish harvested from ARAC. The percentage prevalence of histological alterations showed that fish from Bodo water-body had the worse outcome (25%), followed by Creek Road water-body (21.7%) and ARAC having the best outcome (6.6%). mantle histology has proven to be an explorable biomarker for evaluation of environmental status.