The rapid and continuous growth of Port Harcourt, Nigeria, have contributed to a surge in vehicular traffic, prompting concerns regarding air pollution and its health implications. This study to analyzed the spatial distribution of Particulate Matter (PM) in Port Harcourt and their possible effects on the respiratory health of residents of Port Harcourt Metropolis. Utilizing Geographic Information Systems (GIS) for mapping, air quality monitoring, this study identified pollution hotspots and investigated the prevalence of related respiratory health risks. The results demonstrate significant variations in PM concentrations across the study area, with high-emission zones associated with elevated rates of some respiratory illnesses. These findings emphasize the need for targeted interventions in air quality management and public health policies to reduce the detrimental effects of PM on respiratory health.