Background: Urinary tract infections (UTIs) are prevalent bacterial infections with a considerable impact on healthcare systems. Given the increasing antibiotic resistance globally, particularly in high-frequency regions such as Bangladesh, identifying prevalent pathogens and understanding their resistance patterns is essential for effective treatment. Objective: This study aims to analyze the common pathogens causing UTIs in a private outpatient setting in Bangladesh and evaluate their antibiotic susceptibility profiles to guide empirical therapy and enhance local treatment protocols. Methodology: This three-year prospective observational study (2021-2023) involved 58 UTI patients from a private chamber in Bangladesh. Urine samples were cultured, and bacterial isolates were identified and tested for antibiotic susceptibility to commonly used drugs, including cephalosporins, carbapenems, and fluoroquinolones. Data on organism frequency, resistance, and sensitivity were analyzed. Results: Escherichia coli was the most common pathogen (58.6%), followed by Klebsiella spp. (20.7%) and Methicillin-sensitive Staphylococcus aureus (MSSA) (13.8%). High sensitivity was observed for E. coli to Imipenem (100%) and Meropenem (96%), while significant resistance was noted to Ciprofloxacin (48.5%) and Cefixime (48%). MSSA and Klebsiella spp. similarly showed high susceptibility to carbapenems, with notable resistance to fluoroquinolones in MSSA. Conclusion: The high prevalence of E. coli as the primary UTI pathogen and its resistance patterns in this private setting underscore the necessity of targeted antibiotic selection. The study advocates for carbapenems in cases with suspected resistance and highlights the importance of regular sensitivity testing and antibiotic stewardship in outpatient settings to improve patient outcomes and mitigate resistance.