Infertility has caused a lot of psychological traumas to married women who have not given birth to any child or those who could not give birth again after their first birth at their matrimonial home. Child bearing is the most important reason why most couples got married and if that sole aim is not achieved, it becomes a taboo in some culture in Africa. The aim of this study is to evaluate the Psychological Effects Arising from Infertility Amongst Married Women in South-South Nigeria. This was a cross-sectional study involving 350 married women who were within the age of 18 to 47 years. A well-structured questionnaire was administered to participants. Each participant had one questionnaire to fill appropriately and independently after instructions were given to them by the Research Assistants. The study lasted for a period of 3 months. Statistical analysis of data was done using SPSS Version 25 and P value < 0.05 was considered significant for data. The research findings revealed that the majority (71.4%) of the participants were between 28 – 32 years of age and 57 .1% had tertiary level of education. The study shows that 71.4% of the participants have not got pregnant, 28.6% have gotten their first pregnant, 42.5% had married for a period between 2-4years, 85.7% are eager to get a child, 71.4% do not have a child and 28.6% have only a child. The study also, shows that 85.7% of the participants were bordered and 91.4% were passing through several degree of psychosocial trauma. Again, the research revealed that 82.9% of the participants were passing through pressure or stress and 91.4% of the women have been abused for not conceiving. Also, 85.7% of the participants had increased in their blood pressure after undergoing medical check-up and 91.4% had depression. The study revealed that 71.3% of the women revealed that their husband is planning to take a new wife and 60.5% said their husband have already taken a new wife. The research findings revealed that 82.9% of the participants do not socialize, 74.3% said their husband do not love them again and 57.1% of the participants have pushed out of their matrimonial homes.